Deep Dive In Vitiligo

Navigating Vitiligo Patient Journey Map (Ep. 9)

Navigating vitiligo can feel like trying to find your way through the New York City subway on a Friday eve. But just like any journey, it’s all about finding the right path for you.
In this episode of Deep Dive, we invite you to explore the many-layered experiences of living with vitiligo, discussing both the emotional and logistical challenges. We’ll draw from the Vitiligo Research Foundation’s comprehensive Vitiligo Patient Journey Map, using a subway-style metaphor to illustrate the different routes one can take—whether through repigmentation treatments or embracing self-acceptance.
Throughout this episode, we celebrate empowering stories of individuals who have embraced their vitiligo, discovering unexpected beauty in the process. There’s no single “right way” to manage this condition, and we highlight the importance of finding what resonates with you—both physically and emotionally.
We’ll also talk about the resources and support systems that create a sense of community and resilience among millions worldwide. This episode is an open invitation to explore your unique path, encouraging self-discovery, growth, and perhaps the courage to share your story with others navigating similar journeys.

Outside the Box: Google’s Cracking Down on AI Cheaters

Google’s been working on something cool for AI transparency: an invisible watermark in AI text called SynthID-Text.
They’ve already applied it to 20 million responses from their Gemini chatbot, and users couldn’t tell the difference. This watermark is like a secret stamp that helps flag AI-generated content, opening the door for others to join in and tackle issues like misinformation and AI feedback loops.
For the full scoop and behind-the-scenes insights, check out my latest podcast episode—linked here! Drop your thoughts below! 🍻

Beyond the Surface: What Your Skin Reveals About You (Ep. 8)

What if your skin was more than just a physical barrier? In this thought-provoking episode, we delve into the spiritual and cultural dimensions of skin, exploring how it reflects your inner emotions, beliefs, and even your mental state.
From ancient shamanic practices to cutting-edge psychoneuroimmunology, we uncover how skin conditions have long been viewed as mirrors of spiritual and emotional states. Learn how your mental health can manifest physically through your skin and why practices like mindfulness and gut health are integral to maintaining skin wellness.
We also explore how cultures worldwide use clothing as a “second skin,” expressing deeper values through traditions like head coverings and ritual bathing. Plus, discover how tattoos, piercings, and other adornments serve as powerful tools for storytelling and identity.
Whether you’re fascinated by the connection between mind and body or curious about the cultural narratives woven into skin, this episode will transform how you see and care for yourself—inside and out.
Suggested reading:
Ayahuasca as a Potential Therapy for Vitiligo. A Journey into the Mind-Body Connection

Nailed It: The Surprising Vitiligo Connection (Ep. 7)

Could your nails be revealing more about your health than you think? In this episode, we uncover the surprising connection between vitiligo and nail health, guided by a fascinating clinical study that shows how people with vitiligo often experience unique nail changes, such as longitudinal ridging and absent lunula. 
With input from dermatologists and patient advocates, we also explore how common nail products and their chemical ingredients might exacerbate nail issues for those with vitiligo. Learn how to spot subtle changes in your nails, what they could mean for your overall health, and how small choices—like the nail products you use—can make a big difference.
While the link between vitiligo and nail health is still emerging, this episode is a reminder to stay curious and proactive. Your nails might just be the signal you need to take action and engage with your healthcare team. Tune in, empower yourself with knowledge, and take one step closer to thriving!
 
Suggested reading:
Vitiligo and Your Nails: The Surprising Connection You Need to Know About

The Hidden Burden of Vitiligo: Research and Real-World Stories (Ep. 6)

In this episode, we delve into the profound impact vitiligo has on self-esteem, social interactions, mental health, and overall quality of life. Starting with the basics, we unpack the nature of this autoimmune condition, emphasizing that it affects people of all ethnicities and genders while highlighting the emotional toll of its unpredictable treatments.
Through personal stories and research insights, we explore the psychological challenges of living with vitiligo. From Sarah, a high school student navigating acceptance, to LT, a public figure using his platform to advocate for awareness, these narratives underscore the resilience of individuals facing societal beauty standards. We also discuss how even less visible symptoms can lead to feelings of invalidation, revealing the wide-reaching emotional burden of the condition.
Beyond individual experiences, we broaden the conversation to embrace diversity and challenge traditional notions of beauty. With a focus on early intervention, mental health support, and empathy, we encourage listeners to foster understanding and acceptance—creating a kinder, more inclusive world for everyone.
Suggested reading:
The Real Price Tag of Treating Vitiligo: What You Need to Know

The Vitiligo Diet: Can What You Eat Heal Your Skin? (Ep. 5)

Discover how diet could play a key role in managing vitiligo in this insightful episode. We delve into the science of oxidative stress and the potential benefits of antioxidants like vitamins C, D, and B12 in supporting skin health. From polyphenol-packed coffee, tea, and red wine to the power of fiber-rich whole grains, we explore how specific foods may help regulate the immune system and promote melanocyte function.
We also examine the intriguing connection between gut health and vitiligo, uncovering how a balanced microbiome may influence the condition’s progression. Learn practical ways to support your gut bacteria and overall well-being through thoughtful dietary choices. 
This episode isn’t just about managing symptoms—it’s about empowering yourself with knowledge to take a holistic approach to health and wellness. Whether you’re living with vitiligo or simply curious about the link between diet and skin health, tune in for a deep dive into this fascinating topic.
Suggested reading: 
🥑 Diet for Vitiligo: Eating for Skin Health

1 in 100: Understanding Vitiligo’s Impact on Body and Mind (Ep. 4)

Join us as we untangle the complexities of vitiligo treatment and its far-reaching effects on patients’ lives. From the frustrating trial-and-error of therapies like topical corticosteroids, calcineurin inhibitors, systemic steroids, and phototherapy to the emotional toll of the condition, we explore how vitiligo is far more than skin deep.  
A recent study reveals that nearly 30% of people with vitiligo also have other autoimmune conditions like eczema, Hashimoto’s thyroiditis, or alopecia areata. This highlights the need to view vitiligo holistically, as it not only affects physical health but also significantly impacts mental well-being, contributing to higher rates of depression, anxiety, and insomnia.  
We’ll also discuss why treatment outcomes vary for children and adults, the barriers many face in accessing care, and how vitiligo challenges our healthcare system to provide better, more comprehensive support. Beyond the science, we reflect on how to create a more inclusive and understanding world for those living with vitiligo, offering insights and hope for a brighter future.

Vitiligo Uncovered: Who, Where, and Why? (Ep. 3)

Ever wondered how many people are newly diagnosed with vitiligo each year? In the U.S. alone, the number is around 74,600! In this episode, we unpack the difference between incidence (new cases) and prevalence (total cases), showing how these numbers evolve from childhood to adulthood—don’t worry, it’s simpler than it sounds!  
We also explore how vitiligo affects different racial and ethnic groups, with higher diagnosis rates seen in Hispanic, Latino, and Asian-American communities. From genetic factors to environmental influences and healthcare access, we’ll discuss the many elements that shape how and when vitiligo is diagnosed.  
Plus, we look beyond the U.S., diving into global perspectives and cultural differences in vitiligo experiences. From sunny climates to snowy regions, we examine how factors like sunlight, diet, and chemical exposure impact the condition, providing a comprehensive view of vitiligo’s presence around the world.  
Join us for an enlightening discussion that sheds light on the numbers, stories, and science behind vitiligo, offering fresh insights into this complex and global condition.

From DNA to AI: Progress and Hope in Vitiligo Research (Ep. 2)

Discover the future of vitiligo treatment in our latest episode, where we spotlight cutting-edge therapies transforming care for this complex condition. From Incyte's Opzelura, the first FDA-approved drug for vitiligo, to Temprian Therapeutics’ DNA-based treatments and Clinuvel’s synthetic hormones for full-body repigmentation, we explore the innovations redefining the field.  
Learn how industry leaders like Amgen and Pfizer are moving beyond cosmetic solutions with advanced targeted therapies. Amgen’s AMG-714 blocks interleukin-15 to protect melanocytes, while Pfizer’s oral drug Litfulo targets immune pathways for systemic repigmentation. We also delve into the role of AI in diagnostics, featuring Skinopathy’s groundbreaking collaborations.  
This episode captures the excitement and momentum driving vitiligo research and development. With these advancements, the future looks promising for more effective, accessible, and personalized treatments. Join us for an insightful dive into the breakthroughs offering hope to millions.

Welcome to Deep Dive In Vitiligo! (Ep. 1)

In a world where even dogs have podcasts, it’s time for vitiligo to have its own voice—enter Deep Dive in Vitiligo, a weekly news digest from the frontiers of medicine and science, brought to you by Yan Valle, CEO of the Vitiligo Research Foundation.  
In this debut episode, we set the stage for what this podcast is all about: shedding light on the latest breakthroughs in vitiligo research, debunking myths, and giving this often misunderstood condition the attention it deserves.  
What’s really driving the recent wave of innovations? Are we on the brink of discovering a cure? And how can patients, advocates, and scientists work together to create lasting change? This first episode is your invitation to join a global conversation that will challenge perceptions and inspire action. Whether you’re newly diagnosed, a long-time advocate, or just curious about vitiligo, Deep Dive in Vitiligo is here to be your trusted guide.